Overview
- SupplierGeneTex
- Product NameSOX2 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionThis intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Activating the regenerative potential of Mueller glia cells in a regeneration-deficient retina. Lust K et al., 2018 Jan 29, ElifeRead more
- Critical role of SOX2-IGF2 signaling in aggressiveness of bladder cancer. Chiu YF et al., 2020 May 19, Sci RepRead more
- Crosstalk between SOX2 and cytokine signaling in endometrial carcinoma. Lee CJ et al., 2018 Dec 3, Sci RepRead more
- Neural stem cells induce the formation of their physical niche during organogenesis. Seleit A et al., 2017 Sep 27, ElifeRead more
- Notch signalling patterns retinal composition by regulating atoh7 during post-embryonic growth. Perez Saturnino A et al., 2018 Nov 9, DevelopmentRead more
- Notch/Wnt cross-signalling regulates stemness of dental pulp stem cells through expression of neural crest and core pluripotency factors. Uribe-Etxebarria V et al., 2017 Nov 1, Eur Cell MaterRead more
- Positive feedback of SuFu negating protein 1 on Hedgehog signaling promotes colorectal tumor growth. Yan Z et al., 2021 Feb 19, Cell Death DisRead more