GTX50710 WB Image
GTX50710 WB Image
SP1 (phospho Thr739) antibody
GTX50710
Overview
- SupplierGeneTex
- Product NameSP1 (phospho Thr739) antibody
- Delivery Days Customer10
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- HostRabbit
- IsotypeIgG
- Modification TypePhosphorylated
- Scientific DescriptionThe protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Activation of TWIST1 by COL11A1 promotes chemoresistance and inhibits apoptosis in ovarian cancer cells by modulating NF-kappaB-mediated IKKbeta expression. Wu YH et al., 2017 Dec 1, Int J CancerRead more
- Cystathionine-gamma-lyase ameliorates the histone demethylase JMJD3-mediated autoimmune response in rheumatoid arthritis. Wu W et al., 2019 Aug, Cell Mol ImmunolRead more
- Quercetin Reverses Rat Liver Preneoplastic Lesions Induced by Chemical Carcinogenesis. Carrasco-Torres G et al., 2017, Oxid Med Cell LongevRead more