GTX629890 WB Image
GTX629890 WB Image
SQSTM1 / P62 antibody [GT1478]
GTX629890
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameSQSTM1 / P62 antibody [GT1478]
- Delivery Days Customer9
- CertificationResearch Use Only
- Clone IDGT1478
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Kaposis sarcoma-associated herpesvirus induces Nrf2 activation in latently infected endothelial cells through SQSTM1 phosphorylation and interaction with polyubiquitinated Keap1. Gjyshi O et al., 2015 Feb, J VirolRead more
- The Antihistamine Deptropine Induces Hepatoma Cell Death through Blocking Autophagosome-Lysosome Fusion. Liang YC et al., 2020 Jun 18, Cancers (Basel)Read more
- Transient acceleration of autophagic degradation by pharmacological Nrf2 activation is important for retinal pigment epithelium cell survival. Saito Y et al., 2018 Oct, Redox BiolRead more