GTX100685 ICC/IF Image
GTX100685 ICC/IF Image
SQSTM1 / P62 antibody [N3C1], Internal
GTX100685
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameSQSTM1 / P62 antibody [N3C1], Internal
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.19 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- 1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione Induces G1 Cell Cycle Arrest and Autophagy in HeLa Cervical Cancer Cells. Tsai JH et al., 2016 Aug 5, Int J Mol SciRead more
- A Key Role of DNA Damage-Inducible Transcript 4 (DDIT4) Connects Autophagy and GLUT3-Mediated Stemness To Desensitize Temozolomide Efficacy in Glioblastomas. Ho KH et al., 2020 Jul, NeurotherapeuticsRead more
- A triterpenoid Nrf2 activator, RS9, promotes LC3-associated phagocytosis of photoreceptor outer segments in a p62-independent manner. Saito Y et al., 2020 May 20, Free Radic Biol MedRead more
- Aleuritolic Acid Impaired Autophagic Flux and Induced Apoptosis in Hepatocellular Carcinoma HepG2 Cells. Yi H et al., 2018 Jun 2, MoleculesRead more
- Anticancer Effects of Antihypertensive L-Type Calcium Channel Blockers on Chemoresistant Lung Cancer Cells via Autophagy and Apoptosis. Wong BS et al., 2020, Cancer Manag ResRead more
- Aqueous extract of Polygonum bistorta modulates proteostasis by ROS-induced ER stress in human hepatoma cells. Liu YH et al., 2017 Jan 30, Sci RepRead more
- Aqueous extracts of Paeonia suffruticosa modulates mitochondrial proteostasis by reactive oxygen species-induced endoplasmic reticulum stress in pancreatic cancer cells. Liu YH et al., 2018 Jul 15, PhytomedicineRead more
- Atg5-mediated autophagy deficiency in proximal tubules promotes cell cycle G2/M arrest and renal fibrosis. Li H et al., 2016 Sep, AutophagyRead more
- ATG5-mediated autophagy suppresses NF-kappaB signaling to limit epithelial inflammatory response to kidney injury. Peng X et al., 2019 Mar 15, Cell Death DisRead more
- Autophagic degradation of SQSTM1 inhibits ovarian cancer motility by decreasing DICER1 and AGO2 to induce MIRLET7A-3P. Liao CC et al., 2018, AutophagyRead more