GTX128171 WB Image
GTX128171 WB Image
SQSTM1 / P62 (phospho Ser403) antibody
GTX128171
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameSQSTM1 / P62 (phospho Ser403) antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.08 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Acute resistance exercise induces Sestrin2 phosphorylation and p62 dephosphorylation in human skeletal muscle. Zeng N et al., 2017 Dec, Physiol RepRead more
- Analysis of Cadmium, Epigallocatechin Gallate, and Vitamin C Co-exposure on PC12 Cellular Mechanisms. Bondad SEC et al., 2020 Dec, Biol Trace Elem ResRead more
- Autophagosome immunoisolation from GFP-LC3B mouse tissue. Yao J et al., 2019 Feb, AutophagyRead more
- Glucose starvation induces LKB1-AMPK-mediated MMP-9 expression in cancer cells. Endo H et al., 2018 Jul 4, Sci RepRead more
- HSF1 stress response pathway regulates autophagy receptor SQSTM1/p62-associated proteostasis. Watanabe Y et al., 2017 Jan 2, AutophagyRead more
- Inhibiting autophagy reduces retinal degeneration caused by protein misfolding. Yao J et al., 2018, AutophagyRead more
- p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response. Kageyama S et al., 2021 Jan 4, Nat CommunRead more
- p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response. Kageyama S et al., 2021 Jan 4, Nat CommunRead more
- Polyphenol-enriched azuki bean (Vina angularis) extract reduces the oxidative stress and prevents DNA oxidation in the hearts of streptozotocin-induced early diabetic rats. Kita-Tomihara T et al., 2019 Nov, Int J Food Sci NutrRead more
- PTK2/FAK regulates UPS impairment via SQSTM1/p62 phosphorylation in TARDBP/TDP-43 proteinopathies. Lee S et al., 2020 Aug, AutophagyRead more