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GTX113645 ICC/IF Image
GTX113645 ICC/IF Image
GTX113645 ICC/IF Image

SR-BI antibody

Research Use Only
GTX113645
GeneTex
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    SR-BI antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.12 mg/ml
  • Isotype
    IgG
  • Scientific Description
    Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for hepatitis C virus glycoprotein E2. Binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. Plays an important role in the uptake of HDL cholesteryl ester.
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Combination of apolipoprotein A1-modi liposome-doxorubicin with autophagy inhibitors overcame drug resistance in vitro. Wang B et al., 2014 Dec, J Pharm Sci
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  • Completion of the entire hepatitis C virus life cycle in genetically humanized mice. Dorner M et al., 2013 Sep 12, Nature
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