SR-BI antibody

Catalog number: GTX30467
Brand: GeneTex
Packing: 100 ul
Price: € 500.00
Expected delivery time: 10 days
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Product specifications for - SR-BI antibody

Product group: Antibodies
Category: Primary Antibodies
Application: Flow Cytometry; ImmunoCytoChemistry; ImmunoFluorescence; ImmunoHistoChemistry; ImmunoHistoChemistry Frozen; ImmunoHistoChemistry Parrafin; ImmunoPrecipitation; Neutralisation/Blocking; Western Blot
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purity: Unpurified
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Storage instructions: Keep as concentrated solution. For short-term storage, store at 4°C (up to 10 days). For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Scientific information: 
Scientific info: High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.
"Characterization of hepatitis C virus particle subpopulations reveals multiple usage of the scavenger receptor BI for entry steps." Dao Thi VL et al., 2012 Sep 7, J Biol Chem Read more