STAT2 Antibody, Biotin conjugated

Catalog number: MBS7045909_0,05mg
Brand: MyBioSource
Packing: 0,05 mg
Other sizes: Other sizes available, please contact us.
Price: € 215.00
Expected delivery time: 21 days

Product specifications for - STAT2 Antibody, Biotin conjugated

Product group: Antibodies
Category: Primary Antibodies
Application: ELISA (EIA)
Host: Rabbit
Target: STAT2
Target description: signal transducer and activator of transcription 2
Clonality: Polyclonal
Isotype: IgG
Purity: >95%, Protein G purified
Molecular weight: 97457 Da
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Form supplied: Liquid
Storage instructions: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Scientific information: 
Scientific info: Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Gene ID: 6773
Swiss prot ID: P52630
Additional information: 
Synonyms: IMD44; ISGF-3; P113; STAT113; signal transducer and activator of transcription 2; interferon alpha induced transcriptional activator; signal transducer and activator of transcription 2, 113kDa