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GTX113273 IHC-P Image
GTX113273 IHC-P Image
GTX113273 IHC-P Image

STAT6 antibody

Research Use Only
GTX113273
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    STAT6 antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.27 mg/ml
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • A high-throughput pipeline for validation of antibodies. Sikorski K et al., 2018 Nov, Nat Methods
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  • Cross-talk between human airway epithelial cells and 3T3-J2 feeder cells involves partial activation of human MET by murine HGF. Hynds RE et al., 2018, PLoS One
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  • Proteome profiling of cadmium-induced apoptosis by antibody array analyses in human bronchial epithelial cells. Xu YM et al., 2016 Feb 2, Oncotarget
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  • Solitary Fibrous Tumor of Breast with Anaplastic Areas (Malignant Solitary Fibrous Tumor): A Case Report with Review of Literature. Jung MJ et al., 2019 Jun, J Breast Cancer
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  • Support of BCP-ALL-cells by autologous bone marrow Th-cells involves induction of AID expression but not widespread AID off-target mutagenesis. Traxel S et al., 2021 Aug, Cancer Immunol Immunother
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