GTX109728 IHC-P Image
GTX109728 IHC-P Image
SUCLA2 antibody [N2C3]
GTX109728
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameSUCLA2 antibody [N2C3]
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionSuccinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- A Novel Role for Progesterone Receptor Membrane Component 1 (PGRMC1): A Partner and Regulator of Ferrochelatase. Piel RB 3rd et al., 2016 Sep 20, BiochemistryRead more
- Identification of the Mitochondrial Heme Metabolism Complex. Medlock AE et al., 2015, PLoS OneRead more
- Loss of succinyl-CoA synthase ADP-forming beta subunit disrupts mtDNA stability and mitochondrial dynamics in neurons. Zhao Y et al., 2017 Aug 2, Sci RepRead more