Overview
- SupplierGeneTex
- Product NameT-Plastin antibody [GT3310]
- Delivery Days Customer9
- CertificationResearch Use Only
- Clone IDGT3310
- Concentration2.39 mg/ml
- IsotypeIgG
- Scientific DescriptionPlastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Angiotensin II regulates phosphorylation of actin-associated proteins in human podocytes. Schenk LK et al., 2017 Nov, FASEB JRead more