TCP1 alpha-alpha Antibody (OASE00325)
OASE00325
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityBovine, Canine, C. Elegans, Drosophila, Guinea Pig, Hamster, Human, Monkey, Mouse, Porcine, Rabbit, Rat, Yeast
TargetTcp1
Overview
- SupplierAviva Systems Biology
- Product NameTCP1 alpha-alpha Antibody (OASE00325)
- Delivery Days Customer23
- ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID91a
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID21454
- Target nameTcp1
- Target descriptiont-complex protein 1
- Target synonymsAI528772; c-c; c-cpn; CCT; Cct1; Ccta; CCT-alpha; p6; p63; tailless complex polypeptide 1A; tailless complex polypeptide 1B; t-complex polypeptide 1; T-complex protein 1 subunit alpha; T-complex protein 1 subunit alpha A; T-complex protein 1 subunit alpha B; Tcp-; Tcp-1; TCP-1-A; TCP-1-alpha; TCP-1-B; Tp6; Tp63; TR; TRic
- HostRat
- IsotypeIgG2a
- Scientific DescriptionT-complex polypeptide-1 (TCP1) is a ~60 kDa protein constitutively expressed in almost all eukaryotic cells, and is up-regulated during spermatogenesis. It is found in the cytosol as a subunit of a hetero-oligomeric chaperone that is known to be involved in the folding of actin and tubulin. The family of proteins termed chaperonins act to recognize and stabilize polypeptide intermediates during folding, assembly and disassembly, and share many characteristics with Heat Shock Protein 70 (HSP 70) including high abundance, induction by environmental stress, and ATPase activity. The chaperonin family includes the mitochondrial HSP60, Escherichia coli GroEL, the plastid Rubisco-subunit binding protein, and the archaebacterial protein TF55. The TCP1 sequence shows nearly 40% identity to TF55, but only minimal similarity to HSP60 and GroEL.
- ReactivityBovine, Canine, C. Elegans, Drosophila, Guinea Pig, Hamster, Human, Monkey, Mouse, Porcine, Rabbit, Rat, Yeast
- Storage Instruction-20°C
- UNSPSC12352203