Overview
- SupplierGeneTex
- Product NameTGF beta 1 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.23 mg/ml
- IsotypeIgG
- Scientific DescriptionTGFB is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA (MIM 190170) in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for this peptide. TGFB1, TGFB2 (MIM 190220), and TGFB3 (MIM 190230) all function through the same receptor signaling systems.[supplied by OMIM]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
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- A potential new approach for treating systemic sclerosis: Dedifferentiation of SSc fibroblasts and change in the microenvironment by blocking store-operated Ca2+ entry. Wu CY et al., 2019, PLoS OneRead more
- Exercise-Induced Increases in Insulin Sensitivity After Bariatric Surgery Are Mediated By Muscle Extracellular Matrix Remodeling. Dantas WS et al., 2020 Aug, DiabetesRead more
- Huangqi Shengmai Yin Protects against Radiation-Induced Cardiac Fibrosis Injury by Regulating the TGF-beta1/Smads and MMPs. Gu J et al., 2019, Evid Based Complement Alternat MedRead more
- Human placenta-derived mesenchymal stem cells ameliorate orbital adipogenesis in female mice models of Graves ophthalmopathy. Park M et al., 2019 Aug 9, Stem Cell Res TherRead more
- Iron overloaded polarizes macrophage to proinflammation phenotype through ROS/acetyl-p53 pathway. Zhou Y et al., 2018 Aug, Cancer MedRead more
- miR-4286 is Involved in Connections Between IGF-1 and TGF-beta Signaling for the Mesenchymal Transition and Invasion by Glioblastomas. Ho KH et al., 2022 Apr, Cell Mol NeurobiolRead more
- Normalization of Tumor Vasculature by Oxygen Microbubbles with Ultrasound. Ho YJ et al., 2019, TheranosticsRead more
- Osteosarcoma-Derived Extracellular Vesicles Induce Lung Fibroblast Reprogramming. Mazumdar A et al., 2020 Jul 30, Int J Mol SciRead more
- TGF-beta1 signaling protects retinal ganglion cells from oxidative stress via modulation of the HO-1/Nrf2 pathway. Chen HY et al., 2020 Nov 1, Chem Biol InteractRead more