TIM-1 antibody

Catalog number: GTX85068
Brand: GeneTex
Packing: 100 ug
Price: € 428.00
Expected delivery time: 10 days
Quantity:
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Product specifications for - TIM-1 antibody

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Application: ELISA; ImmunoHistoChemistry; ImmunoHistoChemistry Parrafin; Western Blot
Host: Rabbit
Target: HAVCR1
Target description: hepatitis A virus cellular receptor 1
Clonality: Polyclonal
Isotype: IgG
Properties: 
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 1 mg/ml
Storage instructions: Keep as concentrated solution. For short-term storage, store at 4°C (up to 10 days). For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Scientific information: 
Scientific info: The human form of TIM-1 was initially discovered as a membrane glycoprotein through which the hepatitis A virus can gain entry into a cell. It was also identified as kidney injury molecule 1 (Kim-1), a predicted adhesion molecule that is upregulated on the surfaces of kidney epithelia. It is also expressed on T helper 2 (Th2) cells of the immune system, and following the binding of its natural ligand TIM-4, stimulates T cell expansion and cytokine production in response to viral challenge. It has been suggested that hyperactivation of TIM-1 leads to an increased level of Th2 responsiveness and asthma susceptibility, and antibodies to TIM-1 may therefore be a novel approach to treating asthma.
Gene ID: 26762
Swiss prot ID: Q96D42
Additional information: 
Synonyms: CD365; HAVCR; HAVCR-1; hepatitis A virus cellular receptor 1; kidney injury molecule 1; KIM1; KIM-1; T cell immunoglobin domain and mucin domain protein 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin family member 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1; TIM; TIM1; TIM-1; TIMD1; TIMD-1