TL1A antibody

GeneTex

TL1A antibody

10

Western Blot, ELISA

Research Use Only

Polyclonal

1 mg/ml

Rabbit

IgG

Members in the TNF and its receptor superfamilies regulate immune responses and induce apoptosis. DR3 (also termed Wsl1, Apo3, TRAMP, and LARD) is preferentially expressed by T lymphocytes and upregulated during T cell activation. The ligand for DR3 was recently identified and designated TL1A. TL1A also binds decoy receptor DcR3/TR6, which is expressed in several lung and colon carcinomas and in some normal tissues. TL1A induces apoptosis and NFkappaB activation in DR3 expressing cells, which is antagonized by DcR3. TL1A is upregulated by proinflammatory cytokines TNF and IL1.

Human, Mouse, Rat

2°C to 8°C,-20°C

12352203