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GTX11227 FACS Image
GTX11227 FACS Image
GTX11227 FACS Image

TLR4 antibody [HTA125] (PE)

Research Use Only
GTX11227
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry
Product group Antibodies
ReactivityCanine, Guinea Pig, Human, Porcine, Primate
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    TLR4 antibody [HTA125] (PE)
  • Delivery Days Customer
    10
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    HTA125
  • Conjugate
    RPE
  • Host
    Mouse
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
  • Reactivity
    Canine, Guinea Pig, Human, Porcine, Primate
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Brutons tyrosine kinase mediates FcgammaRIIa/Toll-like receptor-4 receptor crosstalk in human neutrophils. Krupa A et al., 2013 Feb, Am J Respir Cell Mol Biol
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