Bio-Connect
GTX110520 WB Image
GTX110520 WB Image
GTX110520 WB Image

TNF alpha antibody

Research Use Only
GTX110520
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    TNF alpha antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.04 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • VHL Inactivation in Precancerous Kidney Cells Induces an Inflammatory Response via ER Stress-Activated IRE1alpha Signaling. Kuo CY et al., 2017 Jul 1, Cancer Res
    Read more
  • Adipocytes initiate an adipose-cerebral-peripheral sympathetic reflex to induce insulin resistance during high-fat feeding. Cao W et al., 2019 Sep 13, Clin Sci (Lond)
    Read more
  • Aliskiren Improves Ischemia- and Oxygen Glucose Deprivation-Induced Cardiac Injury through Activation of Autophagy and AMP-Activated Protein Kinase. Chiang MH et al., 2017, Front Pharmacol
    Read more
  • Ameliorative effects of Schisandrin B on Schistosoma mansoni-induced hepatic fibrosis in vivo. Lam HYP et al., 2021 Jun, PLoS Negl Trop Dis
    Read more
  • Anti-CD206 antibody-conjugated Fe3O4-based PLGA nanoparticles selectively promote tumor-associated macrophages to polarize to the pro-inflammatory subtype. Zhou Y et al., 2020 Dec, Oncol Lett
    Read more
  • Anti-CD206 antibody-conjugated Fe3O4-based PLGA nanoparticles selectively promote tumor-associated macrophages to polarize to the pro-inflammatory subtype. Zhou Y et al., 2020 Dec, Oncol Lett
    Read more
  • Anti-inflammation performance of curcumin-loaded mesoporous calcium silicate cement. Chen YC et al., 2017 Sep, J Formos Med Assoc
    Read more
  • Apoptosis perturbations and expression of regulatory inflammatory factors in cisplatin-depleted rat livers under l-arginine protection. El-Sayed RM et al., 2019 May, Can J Physiol Pharmacol
    Read more
  • Bisperoxovanadium induces M2-type macrophages and promotes functional recovery after spinal cord injury. Liu J et al., 2019 Dec, Mol Immunol
    Read more
  • Brain-to-cervical lymph node signaling after stroke. Esposito E et al., 2019 Nov 22, Nat Commun
    Read more