TNF Receptor I antibody [6F13]
GTX53102
ApplicationsFlow Cytometry, ImmunoPrecipitation, Western Blot, ELISA
Product group Antibodies
ReactivityMouse
Overview
- SupplierGeneTex
- Product NameTNF Receptor I antibody [6F13]
- Delivery Days Customer10
- ApplicationsFlow Cytometry, ImmunoPrecipitation, Western Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID6F13
- Concentration500 ug/ml
- HostHamster
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mice lacking a functional copy of this gene exhibit impaired immune function. [provided by RefSeq, Sep 2016]
- ReactivityMouse
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203