Bio-Connect

TNF Receptor I antibody [MR1-2]

Research Use Only
GTX54416
GeneTex
ApplicationsFunctional Assay, Flow Cytometry
Product group Antibodies
ReactivityHuman, Monkey, Primate
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    TNF Receptor I antibody [MR1-2]
  • Delivery Days Customer
    10
  • Applications
    Functional Assay, Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    MR1-2
  • Concentration
    100 ug/ml
  • Host
    Mouse
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mutations in this gene underlie tumor necrosis factor receptor-associated periodic syndrome (TRAPS), characterized by fever, abdominal pain and other features. Mutations in this gene may also be associated with multiple sclerosis in human patients. [provided by RefSeq, Sep 2016]
  • Reactivity
    Human, Monkey, Primate
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203