TNFRSF25 Polyclonal Antibody, ALEXA FLUOR(r) 750 Conjugated

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Product specifications for - TNFRSF25 Polyclonal Antibody, ALEXA FLUOR(r) 750 Conjugated

Overview:
Product group:	Antibodies
Category:	Primary Antibodies
Subcategory:	Fluorescent conjugated
Application:	IF(IHC-P)
Application note:	IF(IHC-P)(1:50-200)
Species:	Human
Host:	Rabbit
Target:	TNFRSF25
Target description:	TNF receptor superfamily member 25
Clonality:	Polyclonal
Conjugation:	AlexaFluor 750
Isotype:	IgG

Properties:
Datasheet:	Datasheet
	Research Use Only
UNSPSC:	12352203
Concentration:	1 ug/ul
Storage instructions:	2-¦C to 8-¦C

Scientific information:
Scientific info:	The protein encoded by this gene is a member of theTNF-receptor superfamily. This receptor is expressed preferentiallyin the tissues enriched in lymphocytes, and it may play a role inregulating lymphocyte homeostasis. This receptor has been shown tostimulate NF-kappa B activity and regulate cell apoptosis. Thesignal transduction of this receptor is mediated by various deathdomain containing adaptor proteins. Knockout studies in micesuggested the role of this gene in the removal of self-reactive Tcells in the thymus. Multiple alternatively spliced transcriptvariants of this gene encoding distinct isoforms have beenreported, most of which are potentially secreted molecules. Thealternative splicing of this gene in B and T cells encounters aprogrammed change upon T-cell activation, which predominantlyproduces full-length, membrane bound isoforms, and is thought to beinvolved in controlling lymphocyte proliferation induced by T-cellactivation. [provided by RefSeq, Jul 2008].
Gene ID:	8718

Scientific information:

Scientific info:

The protein encoded by this gene is a member of theTNF-receptor superfamily. This receptor is expressed preferentiallyin the tissues enriched in lymphocytes, and it may play a role inregulating lymphocyte homeostasis. This receptor has been shown tostimulate NF-kappa B activity and regulate cell apoptosis. Thesignal transduction of this receptor is mediated by various deathdomain containing adaptor proteins. Knockout studies in micesuggested the role of this gene in the removal of self-reactive Tcells in the thymus. Multiple alternatively spliced transcriptvariants of this gene encoding distinct isoforms have beenreported, most of which are potentially secreted molecules. Thealternative splicing of this gene in B and T cells encounters aprogrammed change upon T-cell activation, which predominantlyproduces full-length, membrane bound isoforms, and is thought to beinvolved in controlling lymphocyte proliferation induced by T-cellactivation. [provided by RefSeq, Jul 2008].

Gene ID:

8718

Additional information:
Synonyms:	APO-3; DDR3; DR3; LARD; TNFRSF12; TR3; TRAMP; WSL-1; WSL-LR; tumor necrosis factor receptor superfamily member 25; apoptosis inducing receptor; apoptosis-inducing receptor AIR; apoptosis-mediating receptor DR3; apoptosis-mediating receptor TRAMP; death domain receptor 3 soluble form; death receptor beta; lymphocyte-associated receptor of death; protein WSL-1; tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein)

Additional information:

Synonyms:

APO-3; DDR3; DR3; LARD; TNFRSF12; TR3; TRAMP; WSL-1; WSL-LR; tumor necrosis factor receptor superfamily member 25; apoptosis inducing receptor; apoptosis-inducing receptor AIR; apoptosis-mediating receptor DR3; apoptosis-mediating receptor TRAMP; death domain receptor 3 soluble form; death receptor beta; lymphocyte-associated receptor of death; protein WSL-1; tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein)

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TNFRSF25 Polyclonal Antibody, ALEXA FLUOR(r) 750 Conjugated

Product specifications for - TNFRSF25 Polyclonal Antibody, ALEXA FLUOR(r) 750 Conjugated