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TNIK antibody - KO/KD Validated

Research Use Only
GTX13141
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    TNIK antibody - KO/KD Validated
  • Delivery Days Customer
    10
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Germinal center kinases (GCKs), such as TNIK, are characterized by an N-terminal kinase domain and a C-terminal GCK domain that serves a regulatory function (Fu et al., 1999 [PubMed 10521462]).[supplied by OMIM]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Characterization of the ERG-regulated Kinome in Prostate Cancer Identifies TNIK as a Potential Therapeutic Target. Lee RS et al., 2019 Apr, Neoplasia
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  • Extracellular matrix stiffness determines DNA repair efficiency and cellular sensitivity to genotoxic agents. Deng M et al., 2020 Sep, Sci Adv
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  • The essential role of TNIK gene amplification in gastric cancer growth. Yu DH et al., 2014 Feb 24, Oncogenesis
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  • The Ste20 Family Kinases MAP4K4, MINK1, and TNIK Converge to Regulate Stress-Induced JNK Signaling in Neurons. Larhammar M et al., 2017 Nov 15, J Neurosci
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  • Traf2- and Nck-interacting kinase is essential for Wnt signaling and colorectal cancer growth. Shitashige M et al., 2010 Jun 15, Cancer Res
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