TREX1 antibody

GeneTex

TREX1 antibody

9

Research Use Only

0.75 mg/ml

IgG

This gene encodes the major 3->5 DNA exonuclease in human cells. The protein is a non-processive exonuclease that may serve a proofreading function for a human DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3 ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

2°C to 8°C,-20°C

12352203