GTX118736 ICC/IF Image
GTX118736 ICC/IF Image
TSG101 antibody
GTX118736
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameTSG101 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1.09 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Analyses of Intravesicular Exosomal Proteins Using a Nano-Plasmonic System. Park J et al., 2018 Feb 21, ACS PhotonicsRead more
- Analysis of Assembly and Budding of Lujo Virus. Urata S et al., 2015 Dec 30, J VirolRead more
- Cancer-Specifically Re-Spliced TSG101 mRNA Promotes Invasion and Metastasis of Nasopharyngeal Carcinoma. Chua HH et al., 2019 Feb 12, Int J Mol SciRead more
- Colorectal Cancer Cell-Derived Small Extracellular Vesicles Educate Human Fibroblasts to Stimulate Migratory Capacity. Clerici SP et al., 2021, Front Cell Dev BiolRead more
- Cytosolic Genomic DNA functions as a Natural Antisense. Asada K et al., 2018 Jun 4, Sci RepRead more
- EIF3C-enhanced exosome secretion promotes angiogenesis and tumorigenesis of human hepatocellular carcinoma. Lee HY et al., 2018 Mar 2, OncotargetRead more
- Generation of GLA-Knockout Human Embryonic Stem Cell Lines to Model Autophagic Dysfunction and Exosome Secretion in Fabry Disease-Associated Hypertrophic Cardiomyopathy. Song HY et al., 2019 Apr 8, CellsRead more
- Hrs- and CD63-dependent competing mechanisms make different sized endosomal intraluminal vesicles. Edgar JR et al., 2014 Feb, TrafficRead more
- IDOL stimulates clathrin-independent endocytosis and multivesicular body-mediated lysosomal degradation of the low-density lipoprotein receptor. Scotti E et al., 2013 Apr, Mol Cell BiolRead more
- Old world arenaviruses enter the host cell via the multivesicular body and depend on the endosomal sorting complex required for transport. Pasqual G et al., 2011 Sep, PLoS PathogRead more