UCP1 antibody
GTX112784
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameUCP1 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.92 mg/ml
- IsotypeIgG
- Scientific DescriptionMitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- 3-N-butylphthalide protects against high-fat-diet-induced obesity in C57BL/6 mice and increases metabolism in lipid-accumulating cells. Lu KY et al., 2021 Jul, Biomed PharmacotherRead more
- A Lipophilic Fucoxanthin-Rich Phaeodactylum tricornutum Extract Ameliorates Effects of Diet-Induced Obesity in C57BL/6J Mice. Gille A et al., 2019 Apr 6, NutrientsRead more
- Hedgehog signaling in bone regulates whole-body energy metabolism through a bone-adipose endocrine relay mediated by PTHrP and adiponectin. Zhang X et al., 2017 Feb, Cell Death DifferRead more
- High-Fat Diet-Induced Adipose Tissue and Liver Inflammation and Steatosis in Mice Are Reduced by Inhibiting Sialidases. Pilling D et al., 2021 Jan, Am J PatholRead more
- Identification of functional lipid metabolism biomarkers of brown adipose tissue aging. Gohlke S et al., 2019 Jun, Mol MetabRead more
- N-butylidenephthalide ameliorates high-fat diet-induced obesity in mice and promotes browning through adrenergic response/AMPK activation in mouse beige adipocytes. Lu KY et al., 2021 Dec, Biochim Biophys Acta Mol Cell Biol LipidsRead more
- Organic cation transporter 3 (Oct3) is a distinct catecholamines clearance route in adipocytes mediating the beiging of white adipose tissue. Song W et al., 2019 Jan, PLoS BiolRead more
- Serum Amyloid P and a Dendritic Cell-Specific Intercellular Adhesion Molecule-3-Grabbing Nonintegrin Ligand Inhibit High-Fat Diet-Induced Adipose Tissue and Liver Inflammation and Steatosis in Mice. Pilling D et al., 2019 Dec, Am J PatholRead more