UCP1 antibody
GTX131207
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameUCP1 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.37 mg/ml
- IsotypeIgG
- Scientific DescriptionMitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Improved metabolic regulation is associated with retinoblastoma protein gene haploinsufficiency in mice. Petrov PD et al., 2015 Jan 15, Am J Physiol Endocrinol MetabRead more