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GTX103489 WB Image
GTX103489 WB Image
GTX103489 WB Image

VAV1 antibody

Research Use Only
GTX103489
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    VAV1 antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.49 mg/ml
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • A Fucoxanthinol Induces Apoptosis in a Pancreatic Intraepithelial Neoplasia Cell. Terasaki M et al., 2021 Mar-Apr, Cancer Genomics Proteomics
    Read more
  • CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration. Chiang YJ et al., 2013, PLoS One
    Read more