VAV1 (phospho Tyr174) antibody
GTX132787
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameVAV1 (phospho Tyr174) antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.39 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203