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VAV1 (phospho Tyr174) antibody

Research Use Only
GTX132787
GeneTex
Product group Antibodies
Price on request
Packing Size
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Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    VAV1 (phospho Tyr174) antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.39 mg/ml
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203