VEGF Receptor 2 antibody [6B11] - Orthogonal Validated

GeneTex

VEGF Receptor 2 antibody [6B11] - Orthogonal Validated

10

Western Blot, Neutralisation/Blocking, Other Application

Research Use Only

Monoclonal

6B11

Mouse

IgG

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]

Human

2°C to 8°C,-20°C

12352203