VGlut1 antibody, MAb (Biotin)

Biorbyt

VGlut1 antibody, MAb (Biotin)

10

Western Blot, ImmunoHistoChemistry

WB (1:1000) WB, IHC

Research Use Only

Monoclonal

S28-9

1 mg/ml

Biotin

Mouse

IgG1

Mouse monoclonal to VGlut1 (Biotin). VGLUT1 is expressed in a subset of glutamate neurons and transports glutamate into native synaptic vesicles from the brain, exhibiting a conductance for chloride that is blocked by glutamate. Vesicular glutamate transport has a substantially lower apparent affinity than the plasma membrane excitatory amino acid transporters. Glutamate transport by VGLUT1 is saturated with a K(m) of approximately 2 mM, in the same range as transport by synaptic vesicles. Finally, plasma membrane glutamate transporters recognize both aspartate and glutamate as substrates, whereas VGLUT1 does not recognize aspartate..

Human, Mouse, Rat

2°C to 8°C

12352203