GTX109749 WB Image
GTX109749 WB Image
Vinculin antibody [N3C1], Internal
GTX109749
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameVinculin antibody [N3C1], Internal
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.79 mg/ml
- IsotypeIgG
- Scientific DescriptionVinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
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- Progesterone receptor membrane component 1 is involved in oral cancer cell metastasis. Huang HY et al., 2020 Sep, J Cell Mol MedRead more
- Secretome protein signature of human pancreatic cancer stem-like cells. Brandi J et al., 2016 Mar 16, J ProteomicsRead more
- Therapeutic effects of statins against lung adenocarcinoma via p53 mutant-mediated apoptosis. Chou CW et al., 2019 Dec 31, Sci RepRead more
- Tylophorine-based compounds are therapeutic in rheumatoid arthritis by targeting the caprin-1 ribonucleoprotein complex and inhibiting expression of associated c-Myc and HIF-1alpha. Lee YZ et al., 2020 Feb, Pharmacol ResRead more