GTX119416 ICC/IF Image
GTX119416 ICC/IF Image
VPS33A antibody [C1C3]
GTX119416
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameVPS33A antibody [C1C3]
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionVesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and it encodes a protein similar to the yeast class C Vps33 protein. The mammalian class C VPS proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Accumulation of undegraded autophagosomes by expression of dominant-negative STX17 (syntaxin 17) mutants. Uematsu M et al., 2017 Aug 3, AutophagyRead more
- Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity. van der Kant R et al., 2015 Dec 18, J Biol ChemRead more
- LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes. Hubert V et al., 2016 Oct 15, Biol OpenRead more
- Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L. van der Kant R et al., 2013 Aug 1, J Cell SciRead more
- The HOPS complex mediates autophagosome-lysosome fusion through interaction with syntaxin 17. Jiang P et al., 2014 Apr, Mol Biol CellRead more