Overview
- SupplierGeneTex
- Product NameXPA antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- DICER- and MMSET-catalyzed H4K20me2 recruits the nucleotide excision repair factor XPA to DNA damage sites. Chitale S et al., 2018 Feb 5, J Cell BiolRead more
- DICER and ZRF1 contribute to chromatin decondensation during nucleotide excision repair. Chitale S et al., 2017 Jun 2, Nucleic Acids ResRead more
- Transcriptional consequences of XPA disruption in human cell lines. Manandhar M et al., 2017 Sep, DNA Repair (Amst)Read more