Bio-Connect

ZAP70 antibody [SBZAP] (FITC)

Research Use Only
GTX43322
GeneTex
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    ZAP70 antibody [SBZAP] (FITC)
  • Delivery Days Customer
    10
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    SBZAP
  • Concentration
    0.1 mg/ml
  • Host
    Mouse
  • Isotype
    IgG
  • Scientific Description
    This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203