Apoptosis, Necrosis, Cell Death

Working in the apoptosis research area? Bio-Connect offers many different products for apoptosis and necrosis research such as; apoptosis antibodies, inhibitors and activators for apoptosis, apoptotic and necrotic cells detection kits, and apoptosis antibody markers. On this page you will find popular target links to products and background information. If you have any questions or if you are looking for certain products you can contact our techsupport.

Apoptosis (programmed cell death), is a tightly regulated process for dismantling and termination of unneeded, aging, mutated, or infected cells. It is characterized by cell shrinkage, membrane blebbing, phagocytotic engulfment of the fragmented cell, DNA fragmentation, and mitochondrial release of cytochrome C. Dysregulation of cellular death/survival signals is implicated in a broad range of human disease. Deactivation of apoptosis removes the brakes from cellular growth, leading to the unchecked proliferation that a hallmark of cancer, autoimmune disease, and viral infections.

Popular targets in Apoptosis
Annexin VBCL2GranzymePARP
ATG7CaspaseLamp1 & 2SQSTM1
ATG12CathepsinMAP1LC3A / LC3ATNFR1 (CD120a)
ATMCytochrome cMAP1LC3B / LC3BTNFR2 (CD120b)
BADEndonuclease GmTORTRAIL

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