Caspase-1 (mouse) Matched Pair Detection Set

Catalog number: AG-46B-0003-KI01
Brand: AdipoGen Life Sciences
Packing: 1 set
Price: € 560.00
Expected delivery time: 7 days
Quantity:

Product specifications for - Caspase-1 (mouse) Matched Pair Detection Set

Overview: 
Product group: Assays
Category: ELISA / EIA
Application: ELISA
Species: Mouse
Target: Casp1
Target description: caspase 1
Properties: 
Assay Sensitivity: 50pg/ml
Assay Detection Range: 0.15ng/ml to 10ng/ml.
Datasheet: Datasheet
  Research Use Only
UNSPSC: 41116158
Storage instructions: Store at -20°C
Scientific information: 
Scientific info: Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and interleukin-18 (IL-18) and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3/NALP3 responds to a variety of agonists including crystals. The caspase-1 (mouse) Matched Pair Detection Set contains all reagents for the development of a sandwich ELISA to measure caspase-1 (mouse) in cell culture supernatants. This Matched Pair Detection Set is a quantitative detection method, alternative to Western blotting to measure caspase-1 secretion. - Matched Pair Detection Set. Detects mouse Caspase-1 (p10 and p20 domain). Does not detect human Caspase-1. Colorimetric assay. Sample Type: Cell Culture Supernatant. Range: 0.15ng/ml to 10ng/ml. Sensitivity: 50pg/ml. Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and interleukin-18 (IL-18) and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3/NALP3 responds to a variety of agonists including crystals. The caspase-1 (mouse) Matched Pair Detection Set contains all reagents for the development of a sandwich ELISA to measure caspase-1 (mouse) in cell culture supernatants. This Matched Pair Detection Set is a quantitative detection method, alternative to Western blotting to measure caspase-1 secretion.
Gene ID: 12362
Swiss prot ID: P29452
Safety information: 
MSDS: MSDS
Additional information: 
Synonyms: CASP-1; caspase-1; ICE; IL-1 beta-converting enzyme; IL-1B converting enzyme; Il1bc; IL-1BC; interleukin-1 beta convertase; interleukin-1 beta-converting enzyme; p45