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Caspase-1 (mouse) Matched Pair Detection Set

Research Use Only
AG-46B-0003
AdipoGen Life Sciences
ReactivityMouse
Product group Assays
Price on request
Packing Size
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Caspase-1 (mouse) Matched Pair Detection Set
  • Delivery Days Customer
    10
  • Applications
    ELISA
  • Assay Detection Range
    0.15ng/ml to 10ng/ml.
  • Assay Sensitivity
    50pg/ml
  • Assay Specificity
    Detects mouse Caspase-1 (p10 and p20 domain). Does not detect human Caspase-1.
  • Certification
    Research Use Only
  • Scientific Description
    Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and interleukin-18 (IL-18) and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3/NALP3 responds to a variety of agonists including crystals. The caspase-1 (mouse) Matched Pair Detection Set contains all reagents for the development of a sandwich ELISA to measure caspase-1 (mouse) in cell culture supernatants. This Matched Pair Detection Set is a quantitative detection method, alternative to Western blotting to measure caspase-1 secretion. - Matched Pair Detection Set. Detects mouse Caspase-1 (p10 and p20 domain). Does not detect human Caspase-1. Colorimetric assay. Sample Type: Cell Culture Supernatant. Range: 0.15ng/ml to 10ng/ml. Sensitivity: 50pg/ml. Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and interleukin-18 (IL-18) and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3/NALP3 responds to a variety of agonists including crystals. The caspase-1 (mouse) Matched Pair Detection Set contains all reagents for the development of a sandwich ELISA to measure caspase-1 (mouse) in cell culture supernatants. This Matched Pair Detection Set is a quantitative detection method, alternative to Western blotting to measure caspase-1 secretion.
  • Reactivity
    Mouse
  • Storage Instruction
    -20°C
  • UNSPSC
    41116133