EGFR (T790M/C797S/ L858) Kinase Assay Kit
40326
Product group Assays
Overview
- SupplierBPS Bioscience
- Product NameEGFR (T790M/C797S/ L858) Kinase Assay Kit
- Delivery Days Customer7
- CertificationResearch Use Only
- Scientific DescriptionThe epidermal growth factor receptor (EGFR; ErbB-1; HER1) is the cellsurface receptor for members of the epidermal growth factor family. Overexpression and/or hyperactivation of EGFR kinase is associated with several human cancers such as lung, glioblastoma, and epithelian tumors of the neck and head, leading to the development of anticancer therapeutics targeting EGFR. T790M, L858R and C797S mutations in EGFR cause resistance to known EGFR inhibitors. The EGFR(T790M/C797S/L858R) Kinase Assay Kit is designed to identify mutant-selective EGFR kinase inhibitors and to measure EGFR (T790M/C797S/L858R) kinase activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent.
- UNSPSC41116133
References
- Wang, S., et al. J. Hematology & Oncology 9:59 (2016)
- Jia, Y., et al. Nature 534(7605): 129-132 (2016)