Bio-Connect

Human Pro-Collagen I alpha 1 ELISA Kit

Research Use Only
ARG81269
Arigo Biolaboratories
Product group Assays
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    Human Pro-Collagen I alpha 1 ELISA Kit
  • Delivery Days Customer
    23
  • Applications
    ELISA
  • Assay Sensitivity
    15 pg/ml
  • Assay Time
    ~ 3.5 hours
  • Certification
    Research Use Only
  • Scientific Description
    This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    41116133