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METTL3 Chemiluminescent Assay Kit

Research Use Only
79614
BPS Bioscience
Product group Assays
Price on request
Packing Size
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Overview

  • Supplier
    BPS Bioscience
  • Product Name
    METTL3 Chemiluminescent Assay Kit
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Scientific Description
    The METTL3 Chemiluminescent Assay Kit is designed to measure METTL3 activity for screening and profiling applications. The METTL3 Chemiluminescent Assay Kit comes in a convenient format, with 96-well plate precoated with a specific substrate, the antibody against methylated adenosine, a secondary HRP-labeled antibody, S-adenosylmethionine, methyltransferase assay buffer, and purified METTL3 enzyme for 96 enzyme reactions. The key to the METTL3 Chemiluminescent Activity Assay Kit is a highly specific antibody that recognizes N6methylated adenosine. With this kit, only three simple steps are required for methyltransferase detection. First, S-adenosylmethionine is incubated with a sample containing assay buffer and methyltransferase enzyme. Next, primary antibody is added. Finally, the plate is treated with an HRP-labeled secondary antibody followed by addition of the HRP substrate to produce chemiluminescence that can then be measured using a chemiluminescence reader.
  • UNSPSC
    41116133

References

  • Liu, J., et al. Nat Chem Biol. 2014, 10(2): 93-95.