Nampt (Visfatin/PBEF) (mouse/rat) Dual ELISA Kit

Catalog number: AG-45A-0007YEK-KI01
Brand: AdipoGen Life Sciences
Packing: 96 wells
Price: € 670.00
Expected delivery time: 7 days
Quantity:

Product specifications for - Nampt (Visfatin/PBEF) (mouse/rat) Dual ELISA Kit

Overview: 
Product group: Assays
Category: ELISA / EIA
Application: ELISA
Species: Mouse, Rat
Target: Nampt
Target description: nicotinamide phosphoribosyltransferase
Properties: 
Assay Sensitivity: 50pg/ml
Assay Detection Range: 0.5 to 32ng/ml
Datasheet: Datasheet
  Research Use Only
UNSPSC: 41116158
Storage instructions: 2-¦C to 8-¦C
Scientific information: 
Scientific info: ELISA Assay. Detects mouse and rat Nampt. Does not cross-react with human Nampt, mouse adiponectin, mouse resistin, mouse vaspin or mouse RBP4. Colorimetric assay. Sample Types: Serum. Range: 0.5 to 32ng/ml. Sensitivity: 50pg/ml. Nicotinamide phosphoribosyltransferase (Nampt; pre-B cell colony-enhancing factor; PBEF; Visfatin) is an 52kDA adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. It has been shown that Nampt expression is increased in different diseases, like diabetes, obesity, fetal growth retardation, sepsis, inflammatory bowel disease, Crohns disease and rheumatoid arthritis. Furthermore, Nampt might be a marker of pre-eclampsia and of endothelial health. - Nicotinamide phosphoribosyltransferase (Nampt; pre-B cell colony-enhancing factor; PBEF; Visfatin) is an 52kDA adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. It has been shown that Nampt expression is increased in different diseases, like diabetes, obesity, fetal growth retardation, sepsis, inflammatory bowel disease, Crohns disease and rheumatoid arthritis. Furthermore, Nampt might be a marker of pre-eclampsia and of endothelial health.
Gene ID: 59027
Swiss prot ID: Q99KQ4
Safety information: 
MSDS: MSDS
Hazard information: Non-hazardous
Additional information: 
Synonyms: AG-45A-0007YEK-KI01; AdipoGen Life Sciences; 1110035O14Rik; AI314458; AI480535; NAmPRTase; nicotinamide phosphoribosyltransferase; Pbef; Pbef1; pre-B-cell colony-enhancing factor 1 homolog; Visfatin
Nampt secreted from cardiomyocytes promotes development of cardiac hypertrophy and adverse ventricular remodeling: V.B. Pillai, et al.; Am. J. Physiol. Heart Circ. Physiol. 304, H415 (2013) Read more
Hepatectomy-related hypophosphatemia: a novel phosphaturic factor in the liver-kidney axis: K. Nomura, et al.; J. Am. Soc. Nephrol. 25, 761 (2014) Read more
Nicotinamide phosphoribosyltransferase inhibitor is a novel therapeutic candidate in murine models of inflammatory lung injury: L. Moreno-Vinasco, et al.; Am. J. Respir. Cell Mol. Biol. 51, 223 (2014) Read more