PKG Substrate

Catalog number: HY-P1561_1mg
Brand: MedChem Express
Packing: 1 mg
Other sizes: 5 mg
Price: € 142.00
Expected delivery time: 10 days

Product specifications for - PKG Substrate

Product group: Chemicals
Category: Other
Molecular Formula: C35H67N17O11
Molecular weight: 902.01
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352200
Scientific information: 
Scientific info: PKG Substrate is a selective substrate for cGMP-dependent protein kinase (PKG). IC50 & Target: PKG In Vitro: Incorporation ofATP into the synthetic peptide PKG substrate RKRSRAE is measured. N6-benzyl-ATP inhibits kinase activity of PKG Ialpha gatekeeper mutants but not WT. The serotonin transporter (SERT) is responsible for reuptake of serotonin (5-hydroxytryptamine) after its exocytotic release from neurons. SERT is regulated by several processes, including a cyclic GMP signaling pathway involving nitric oxide synthase, guanylyl cyclase, and PKG.
Safety information: