Senescence Assay Kit

Catalog number: GXS0003
Brand: OZ Biosciences
Packing: 1 kit
Price: € 203.00
Expected delivery time: 5 days

Product specifications for - Senescence Assay Kit

Product group: Assays
Category: Cell based assays
Subcategory: Apoptosis
Datasheet: Datasheet
  Research Use Only
UNSPSC: 41116133
Scientific information: 
Scientific info: Senescence Kit is ideal when cells in culture showed abnormalities typical of the Hayflick limit, after a long period of normal growth. The cells vary in size and shape, the cytoplasm begins to be granular with many cell inclusions and debris formed in the medium. Senescence goes with decreasing of proliferation potential, telomere shortening and impairment of cell function (i.e decrease of differentiation potential of stem cells). During senescence in mammalian cells, an endogenous lysosomal b-galactosidase is over-expressed and is accumulated within the aging cells. The presence of this b-Gal activity is a marker of aging cell population in vitro.

OZ Biosciences Cellular Senescence Kit allows visualization of ageing cells and is:
  • Simple and Rapid
  • Ready-to-use
  • Economical
Additional information: 
Synonyms: GXS0003; OZ Biosciences
Matsumura K, Nakata S, Taniguchi K, et al. Depletion of γ-glutamylcyclotransferase inhibits breast cancer cell growth via cellular senescence induction mediated by CDK inhibitor upregulation. BMC Cancer. 2016;16(1):748. Read more
Mishel S, Shneyer B, Korsensky L, et al. Delivery of the gene encoding the tumor suppressor Sef into prostate tumors by therapeutic-ultrasound inhibits both tumor angiogenesis and growth. Sci Rep. 2017;7(1):15060. Read more
Mitkin NA, Muratova AM, Korneev KV, et al. Protective C allele of the single-nucleotide polymorphism rs1335532 is associated with strong binding of Ascl2 transcription factor and elevated CD58 expression in B-cells. Biochim Biophys Acta Mol Basis Dis. 2018;1864(10):3211-3220. Read more
Mito A, Nakano Y, Saitoh T, et al. Lectin ZG16p inhibits proliferation of human colorectal cancer cells via its carbohydrate-binding sites. Glycobiology. 2018;28(1):21-31. Read more
Miyazaki S, Kakutani K, Yurube T, et al. Recombinant human SIRT1 protects against nutrient deprivation-induced mitochondrial apoptosis through autophagy induction in human intervertebral disc nucleus pulposus cells. Arthritis Res Ther. 2015;17:253. Read more
Mizuno H, Taketomi A. MicroRNA-101 inhibits the expression of Rhes, a striatal-enriched small G-protein, at the post-transcriptional level in vitro. BMC Res Notes. 2018;11(1):528. Read more
Mizutani T, Fukushi S, Ishii K, et al. Mechanisms of establishment of persistent SARS-CoV-infected cells. Biochem Biophys Res Commun. 2006;347(1):261-5. Read more