hPDE1B-HEK293 Cell line

Catalog number: 60402
Brand: BPS Bioscience
Packing: 2 Vials
Price: € 9342.00
Expected delivery time: 7 days

Product specifications for - hPDE1B-HEK293 Cell line

Product group: Cell Culture
Category: Cell lines
Application note: Useful to monitor cAMP and PDE1B signaling pathway activity and to screen activators or inhibitors of PDE1B.
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352207
Form supplied: aqueous solution containing DMSO
Storage instructions: Store in liquid nitrogen immediately upon receipt.
Scientific information: 
Scientific info: Recombinant HEK293 cell line expressing human PDE1B (phosphodiesterase 1B, accession number NM_000924). N-terminal His-tagged human PDE1B has been stably expressed in HEK293 cell line and its expression was confirmed by Western blotting. The function of PDE1B was characterized by a cell-based cGMP assay. In this assay system, cells co-express atrial natriuretic peptide (ANP) receptor A (a guanylate cyclase), cyclic nucleotide5gated cation channel CNGA2, and the photoprotein aequorin. Intracellular cGMP level is monitored via aequorin luminescence induced by Ca2+ influx through CNGA2, acting as the intracellular cGMP sensor.
Swiss prot ID: Q01064
Additional information: 
Synonyms: 60402; BPS Bioscience