25-Hydroxycholesterol [2140-46-7]

MedChem Express

25-Hydroxycholesterol [2140-46-7]

10

2140-46-7

98%

C27H46O2

402.65

25-Hydroxycholesterol is a metabolite of cholesterol that is produced and secreted by macrophages in response to Toll-like receptor (TLR) activation. 25-hydroxycholesterol is a potent (EC50~65 nM) and selective suppressor of IgA production by B cells.

CC(C)(O)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C

2°C to 8°C,-20°C,-80°C

12352200