A-317491 sodium salt hydrate
HY-15568A
Overview
- SupplierMedChem Express
- Product NameA-317491 sodium salt hydrate
- Delivery Days Customer10
- CertificationResearch Use Only
- Estimated Purity99.63%
- Molecular FormulaC33H29NNaO9
- Molecular Weight606.57
- Scientific DescriptionA-317491 sodium salt hydrate is a potent, selective and non-nucleotide antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively. A-317491 sodium salt hydrate is highly selective (IC50>10 microM) over other P2 receptors and other neurotransmitter receptors, ion channels, and enzymes. A-317491 sodium salt hydrate reduces inflammatory and neuropathic pain by blocking P2X3 and P2X2/3 receptor-mediated calcium flux.
- SMILESO=C(C1=CC(C(N(CC2=CC=CC(OC3=CC=CC=C3)=C2)[C@H]4CCCC5=C4C=CC=C5)=O)=C(C(O)=O)C=C1C(O)=O)O.[Na].O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200