Abiraterone [154229-19-3]

MedChem Express

Abiraterone [154229-19-3]

10

154229-19-3

95.8%

C24H31NO

349.51

Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity, which inhibits both the 17alpha-hydroxylase and 17,20-lyase activity of the cytochrome p450 enzyme CYP17 with IC50s of 2.5 nM and 15 nM, respectively.

C[C@@]12C(C3=CN=CC=C3)=CC[C@]1([C@@]4(CC=C5[C@@](C)([C@]4(CC2)[H])CC[C@@H](C5)O)[H])[H]

2°C to 8°C,-20°C,-80°C

12352200