Dasabuvir [1132935-63-7]

MedChem Express

Dasabuvir [1132935-63-7]

10

1132935-63-7

Research Use Only

98%

C26H27N3O5S

493.57

Dasabuvir (ABT-333) is a nonnucleoside hepatitis C virus (HCV) polymerase inhibitor. Dasabuvir inhibits RNA-dependent RNA polymerase encoded by the HCV NS5B gene. Dasabuvir inhibits genotype 1a (strain H77) and 1b (strain Con1) replicons, with EC50 values of 7.7 and 1.8 nM, respectively.

CS(=O)(NC1=CC=C2C=C(C3=CC(N(C(N4)=O)C=CC4=O)=CC(C(C)(C)C)=C3OC)C=CC2=C1)=O

2°C to 8°C,-20°C,-80°C

12352200