AC-55541 [916170-19-9]

MedChem Express

AC-55541 [916170-19-9]

10

916170-19-9

Research Use Only

99.25%

C25H20BrN5O3

518.36

AC-55541 is a highly selective protease-activated receptor 2 (PAR2) agonist (pEC50=6.7), displays no activity at other PAR subtypes or at over 30 other receptors involved in nociception and inflammation. AC-55541 has pEC50 values of 5.9 and 6.6 in PI hydrolysis assays and Ca2+ mobilization assays and exhibits pronociceptive activity in vivo.

O=C(NC(C(C1=CC=CC=C12)=NNC2=O)C(N/N=C(C)/C3=CC=CC(Br)=C3)=O)C4=CC=CC=C4

2°C to 8°C,-20°C,-80°C

12352200