Bio-Connect

Aprocitentan [1103522-45-7]

Research Use Only
HY-15895
MedChem Express
CAS Number1103522-45-7
Product group Chemicals
Estimated Purity98.03%
Molecular Weight546.19
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    MedChem Express
  • Product Name
    Aprocitentan [1103522-45-7]
  • Delivery Days Customer
    10
  • CAS Number
    1103522-45-7
  • Certification
    Research Use Only
  • Estimated Purity
    98.03%
  • Molecular Formula
    C16H14Br2N6O4S
  • Molecular Weight
    546.19
  • Scientific Description
    Aprocitentan (ACT-132577) is the major and pharmacologically active metabolite of Macitentan. Aprocitentan is dual ETA/ETB antagonist with IC50s of 3.4 nM and 987 nM, and pA2 valus of 6.7 and 5.5, respectively.
  • SMILES
    O=S(N)(NC1=NC=NC(OCCOC2=NC=C(Br)C=N2)=C1C3=CC=C(Br)C=C3)=O
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200