Adapalene [106685-40-9]

MedChem Express

Adapalene [106685-40-9]

10

106685-40-9

Research Use Only

98%

C28H28O3

412.52

Adapalene (CD271), a third-generation synthetic retinoid, is widely used for the research of acne. Adapalene is a potent RAR agonist, with AC50s of 2.3 nM, 9.3 nM, and 22 nM for RARbeta, RARgamma, RARalpha, respectively. Adapalene also inhibits the enzymatic activity of GOT1 in a non-competitive manner. Adapalene exhibits anti-tumor activity.

COC1=C(C23CC4CC(C3)CC(C2)C4)C=C(C5=CC6=C(C=C(C(O)=O)C=C6)C=C5)C=C1

2°C to 8°C,-20°C,-80°C

12352200