AGN-195183 [367273-07-2]

MedChem Express

AGN-195183 [367273-07-2]

10

367273-07-2

Research Use Only

98.1%

C22H22ClF2NO4

437.86

AGN-195183 (IRX-5183) is a potent and selective agonist of RARalpha (Kd=3 nM) with improved binding selectivity relative to AGN 193836. AGN-195183 has no activity on RARbeta/gamma.

O=C(O)C1=C(F)C=C(NC(C2=C(O)C(Cl)=C3C(C)(C)CCC(C)(C)C3=C2)=O)C=C1F

2°C to 8°C,-20°C,-80°C

12352200